peptide therapeutics

Australia's medicines regulator has issued a safety alert regarding the surge in unregulated peptides promoted online for anti-ageing and performance enhancement. These unverified products, often injected, lack TGA evaluation for safety, quality, or effectiveness, posing significant risks of contamination, infection, and unknown side effects. The gap between hype and evidence is dangerously wide.

A new study has shown how researchers studying snake venom found ways of potentially impacting future therapeutic applications for preventing and treating neurological disorders such as Parkinson’s disease (PD) and Alzheimer’s disease (AD).

Soon, snake venom could help treat neurodegenerative disorders like Parkinson’s disease and Alzheimer’s. Researchers from the Institute of Advanced Study in Science and Technology (IASST), Guwahati, have designed two peptides inspired by non-toxic proteins present in snake venom.

According to the researchers, including those from the University of Toronto in Canada, when the two peptides are combined, they work together to penetrate a cell's membrane in order to dampen an acute inflammatory response.

Bee venom could be a potential source for treatment for Covid-19 infection. City-based CSIR-Centre for Cellular and Molecular Biology (CCMB) researchers found the anti-bacterial peptides from bee venom decreased the viral load of coronavirus.

CAMH's Fang Liu developed a protein peptide that provided a highly targeted approach to treating depression that she hopes will have minimal side effects.

The research team headed by professor Vibin Ramakrishnan and professor HarshalNemade, of IIT Guwahati studied the neurochemical principles of Alzheimer’s, and explored new ways to prevent accumulation of neurotoxic molecules in the brain that are associated with short-term memory loss.

Speaking on 'Regulating gene expression by designed synthetic molecules', he emphasised the pivotal role of transcription factors in the area of cancer.

Dr Reddy's introduced its second bio-generic product rituximab, a monoclonal antibody used in the treatment of non-hodgkins lymphoma, last year. The drug contributed over Rs 15 crore in revenues in 2007-08.

Researchers at Indian Institute of Technology Guwahati are working on out-of-the-box ideas that can help prevent or reduce short-term memory losses associated with Alzheimer’s disease.

A young Indian scientist has developed a potential non-insulin drug candidate for diabetic patients that can help eliminate the risk of low-blood glucose shock in case of an insulin overdose.

Injecting a specific gene directly into the brain may offer a potential new therapy for halting the progress of Alzheimer's disease, especially when treated at an early stage, a new study has claimed.

New Delhi, Jan 7 () Aurobindo Pharma is focussing on building a diverse speciality portfolio of nearly 150 products with an addressable market size of USD 118.2 billion in the next three financial years, the drug firm said in an investor presentation on Monday.

The platypus, a unique mammal, possesses a venom system in adult males delivered via hind leg spurs. This venom, primarily for social dominance, causes intense, persistent pain in humans due to its unusual peptide composition. Research into these peptides offers insights into mammalian venom evolution and potential new pain management drugs.

Snake venom, a complex blend of proteins and enzymes, evolved over millions of years for predation and defence. While it can cause severe harm, its components have led to medical breakthroughs, such as antivenom and treatments for hypertension, heart disease, and cancer. Ethical venom extraction remains crucial alongside conservation efforts.