gene therapy

A groundbreaking gene therapy, VERVE-102, has shown promise in reducing "bad" cholesterol by up to 62% with a single injection, potentially transforming heart health treatment. This one-off infusion targets the liver's cholesterol production, offering a sustained solution for patients struggling with daily medication adherence and side effects.

An experimental Eli Lilly gene-editing drug sharply lowers LDL cholesterol in an early trial, raising hopes of a one-time treatment for high-risk heart patients, but larger studies must still prove long-term safety

Russia is investing billions in a state-backed initiative focused on longevity, exploring gene therapy, organ printing, and cryotherapy. This ambition, fueled by President Putin's personal fascination with extending life and power, aims to overcome aging. Despite bold claims, critics question the scientific validity, while Russia grapples with low life expectancy.

A groundbreaking international trial, Optima, reveals a genomic test, Prosigna, can identify breast cancer patients unlikely to benefit from chemotherapy. This precision oncology approach analyzes tumor genes, potentially sparing thousands of women the harsh side effects of chemo while maintaining similar survival rates. The findings promise a more personalized and less burdensome cancer treatment future.

A select number of physicians are using pharmacogenomic and whole-genome data to refine treatment plans, particularly for cardiology and oncology. The catch: The test isn't on any standard panel, but this may be the beginning of an effective way of practicing medicine.

In a breakthrough, Shanghai scientists have cultivated the world's first lab-grown sinoatrial node using human stem cells. This tiny, self-beating organoid mimics the heart's natural pacemaker, offering immense potential for studying cardiac issues and developing advanced biological pacemaker therapies. Researchers successfully replicated embryonic development signals, paving the way for future transplant strategies.

Centre To Focus On Early Diagnosis, Newborn Screening, And Long-Term Care

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Families and researchers are advocating for Huntington's disease to be recognized as a rare disease in India to establish a much-needed registry. This recognition is crucial for quantifying patient numbers, improving treatment accessibility, and securing coverage under national health policies, offering hope for affected individuals and families.

Roche’s subcutaneous Tecentriq can be given in about seven minutes, cutting infusion time dramatically. But its impact in India will depend on patient selection, local post-marketing data, hospital readiness and whether a costly immunotherapy can become accessible beyond large private cancer centres

Doctors say that if there’s a history of heart attacks in your family, routine tests may not capture how much at risk you are even at young ages

Persistent bloating and abdominal fullness, often dismissed as common issues, could signal ovarian cancer. Experts urge women not to normalize these symptoms, as they may indicate a serious condition. Early detection, characterized by a cluster of persistent signs like pelvic pain and unexplained fatigue, significantly improves survival rates. Vigilance and prompt medical consultation are crucial.

Initially treated for tuberculosis, a young patient’s life took a dramatic turn when advanced diagnostics uncovered a rare cancer mutation, leading to a targeted therapy that changed everything.

A groundbreaking gene therapy trial has successfully restored hearing in individuals with a rare form of congenital deafness. Researchers delivered a functional OTOF gene via a single injection, enabling speech recognition in some patients within weeks. This marks a significant shift towards correcting the root cause of genetic hearing loss.

Haemophilia, a genetic bleeding disorder, often goes undiagnosed in India, leaving many families unaware of its signs. Early detection of symptoms like prolonged bleeding, frequent bruising, and swollen joints is crucial. Timely treatment and preventive care, including factor replacement and physiotherapy, can significantly improve quality of life, enabling individuals to lead active lives despite the condition.

A groundbreaking instance of sustained HIV remission post-stem cell transplant is transforming our understanding of the virus. Although it doesn't serve as a universal cure, the connection to an unusual genetic mutation opens up exciting new avenues. Scientists are delving into gene modification and cutting-edge therapies to potentially harness these remission advantages, sparking optimism for future treatment options.

In a pioneering experiment, Spanish scientists claim to have extended the lifespan of aging mice by up to 24%, using a single gene therapy treatment.

Explore the revolutionary field of gene therapy, where the power of DNA is harnessed to treat genetic disorders and potentially cure previously incurable diseases.

A groundbreaking topical gene therapy for 'butterfly skin disease' has transformed rare disease treatment. Suma Krishnan's innovative approach, applying genetic medicine directly to the skin, led to the FDA-approved Vyjuvek. This breakthrough, developed in her fifties, offers hope and a new era of targeted care for patients suffering from this painful inherited condition.

Injecting a specific gene directly into the brain may offer a potential new therapy for halting the progress of Alzheimer's disease, especially when treated at an early stage, a new study has claimed.