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Why is your Vitamin D level low? 5 reasons other than lack of sunlight exposure

TOI Lifestyle Desk
| ETimes.in | Last updated on - Jul 15, 2025, 09:17 IST
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What are the reasons that one might have low levels of vitamin D


Vitamin D deficiency has quietly become one of the most common nutritional shortfalls worldwide. It often wears no symptoms until it begins to affect bone health, mood, immunity, or energy levels. The first thing that comes to mind when thinking of low vitamin D is "not getting enough sun." But here's the truth: low sunlight exposure is just one chapter of the story. There are several other valid reasons that might be reducing vitamin D levels, even in individuals who spend time outdoors or take supplements.
Here are 5 such reasons that don’t get talked about often.

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The gut might not be absorbing it well

At the surface, one might assume that eating vitamin D-rich foods or taking a supplement should be enough. But here’s the twist: Vitamin D is fat-soluble. This means it needs proper fat digestion and a healthy gut to be absorbed.

In cases of conditions like celiac disease, Crohn’s disease, or even undiagnosed IBS, the intestines might not absorb nutrients efficiently. A study, observed that patients with inflammatory bowel diseases had significantly lower levels of vitamin D, despite sufficient dietary intake.

The truth is, even the most nutritious meal won’t help if the gut isn't functioning well. It's not always about what goes in, but what actually gets absorbed.

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Certain medications can lower vitamin D levels

Not often considered, but several commonly prescribed medications might be interfering with vitamin D metabolism. For example:

Corticosteroids (used in asthma or arthritis) can reduce calcium absorption and impair vitamin D activity.

Anti-epileptic drugs like phenytoin or phenobarbital can increase the breakdown of vitamin D in the liver.

Weight-loss drugs that reduce fat absorption can inadvertently lower vitamin D levels too.

According to research, prolonged use of these drugs can be a silent culprit behind unexplained vitamin D deficiency.

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High body fat can trap vitamin D

Here’s an unusual fact: vitamin D loves fat. It binds to fat tissues and gets stored there. But that’s not always good news. In individuals with higher body fat percentages, vitamin D becomes less bioavailable, meaning it gets locked away and isn’t accessible for the body to use.

A study noted that people with obesity may need 2-3 times more vitamin D to maintain normal blood levels. So, it’s not always about intake, but distribution and availability inside the body. The sunshine vitamin doesn’t shine equally for all.

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The liver and kidney play a bigger role than most think

The common assumption is that vitamin D is made in the skin from sunlight, and that’s the end of the story. But in reality, that’s just the first step. After being produced in the skin, vitamin D goes to the liver where it is converted into a storage form, and then to the kidneys, where it’s turned into the active form the body can use.

Any mild dysfunction in the liver (due to fatty liver, alcohol use, or hepatitis) or in the kidneys (age-related decline or underlying disease) can disrupt this process silently.

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Genetic variants that affect vitamin D receptors

This one’s rarely spoken about but incredibly eye-opening. Some individuals may have genetic variations in the vitamin D receptor (VDR) gene, which can reduce how effectively vitamin D is used by the body, even if levels appear normal in a blood test.

According to a study, certain VDR polymorphisms are linked to reduced immune response and lower vitamin D efficacy. So, someone may be doing everything right, getting sun, eating well, taking supplements, and still not seeing benefits due to these subtle genetic differences.

Science is only beginning to uncover the layers of this. But it’s a reminder that health is never one-size-fits-all.



[Disclaimer: This article is intended for informational purposes only and does not substitute professional medical advice. Any concerns about vitamin D deficiency should be discussed with a qualified healthcare provider. All facts and studies mentioned here are verified from credible medical sources.]


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Diet

A diet that lacks vitamin D-rich foods, especially if the individual does not get enough exposure can contribute to low levels of this nutrient. Incorporating a nutritious and well-balanced diet is important.

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