Why weight loss from new obesity drugs doesn’t easily last

Team TOI Plus
Jan 14, 2026 | 18:21 IST

Drawing on data from over 9,000 patients, a new study tracks what happens after weight-loss injections are stopped and explains why biology, not willpower, largely determines whether the kilos stay off

If you have been taking a weekly injection prescribed for weight loss, the change can feel transformative.

Hunger recedes into the background. Portion sizes shrink without constant effort. Cravings soften. The weighing scale begins to move steadily downward. Blood sugar readings often improve, and blood pressure may follow.
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