What is testosterone therapy? Is it safe?

'Titanic' actor Kate Winslet recently spoke about testosterone therapy and there has been a buzz around it since then. Kate opened up on this treatment process during an episode of 'How to Fail' podcast.

So, what is testosterone therapy?

As the name suggests, testosterone therapy involves treatment using testosterone hormone. Testosterone is used to treat sexual dysfunction in both men and women. The treatment includes enhanced libido, increase in bone mass and overall well-being.

In the podcast, Winslet said that testosterone therapy can be a solution for women who experience a drop in libido. “Women have testosterone in their bodies, and when it runs out, like eggs, it’s gone. Once it’s gone, you can replace it, and it can help you feel sexy again,” she said.

Is testosterone therapy safe for women?

"The hormone testosterone may boost sex drive for some women after menopause. But there is little research on how safe it is and how well it works over the long term. It also can cause side effects," as per a report in MayoClinic. "Due to a lack of research on long term safety, testosterone therapy is not right for women with heart, blood vessel or liver disease," it adds.

"Testosterone therapy is not a fountain of youth. There is no proof that it will restore you to the level of physical fitness or sexual function of your youth, make you live longer, prevent heart disease or prostate cancer, or improve your memory or mental sharpness," a Harvard report says.

How is testosterone therapy done?

Testosterone therapy is done in several ways; most common forms include injections, patches, gels, and oral medications.

Testosterone injections are usually administered intramuscularly, either weekly or bi-weekly, into the buttocks or thigh. This method allows for a rapid increase in testosterone levels but may require frequent visits to a healthcare provider.

Transdermal patches are applied to the skin, typically on the back, abdomen, or thighs, where they release testosterone steadily over 24 hours. Patches need to be rotated to prevent skin irritation and should be worn continuously except during swimming or bathing.


Topical gels are another option, applied daily to clean, dry skin on areas such as the shoulders, upper arms, or abdomen. The gel is absorbed into the bloodstream, providing a consistent level of testosterone. Users must avoid skin-to-skin contact with others where the gel has been applied to prevent accidental transfer.

Oral testosterone formulations are available but less commonly used due to potential liver toxicity and variable absorption rates. Each method has its benefits and drawbacks, so choosing the right one involves a discussion with a healthcare provider to assess individual needs and preferences.