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This story is from February 24, 2009
PU microbiology profs work at bettering antibiotics
Indian Council of Medical Research, which is searching for ways to keep these side effects at bay, has involved Panjab University departments of microbiology and biotechnology in this work.
Three PU microbiology professors are working on separate approaches to reduce the side effects of antibiotics and help in finding new ways to combat resistance towards these drugs among bacteria.
Department���s professor Praveen Rishi said, ������Improper and excessive use of antibiotics can have adverse effects on human beings ranging from fever and nausea to allergic reactions.������
Her research has revealed that biocompatible agents (which the body has less trouble accepting) can substitute the use of antibiotics. In her study, she took extracts of neem, aloe vera and crucumin and the results showed that such agents were very effective in replacing antibiotics.
She said excessive use of antibiotics led to persistent and chronic diseases. Moreover, it was observed that antibiotic resistance was developing rampantly in pathogenic bacteria.
Kusum Harjai of the department has found that probiotic (human friendly) bacteria could be used as delivery agents for intercepting molecules. Humans regularly consume probiotics in various forms of fermented and cultured foods and drinks - such as yogurt, cheese, sauerkraut and pickles.
Sanjay Chhibber���s research has found that bacteriophage treatment ( using viruses that infect bacteria) was a good substitute for antibiotics.
His work was also published in an international journal.
The department���s chairman, Praveen Sharma, said it was handling various projects worth Rs 2.5 crore.
He said the department recently secured a patent along with Institute of Microbial Technology (IMTECH), Chandigarh, for developing a process for producing digestive enzyme a-amylase.
It has a technological tie-up with Cadila group. The department also got a joint patent with Thapar Corporate Centre, Patiala, for bio-bleaching of eucalyptus pulp.
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